Life+Cycle

=Life Cycle=

Replication cycle of the viruses in host
Replication of coronavirus involves the generation and translation of genomic and subgenomic viral mRNAs. The replicaiton takes place in the cytoplasm. Virus entry is by receptor-mediated fusion of the virion with the plasma membrane followed by the release of genomic RNA. Only one protein is translated from each sub-genomic mRNA. High rates of mutations occur as a result of the high error frequencies of the RNA polymerase.



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Hosts
Vertebrates, such as humans and [|civet cat], are host to the viruses belonging to Coronaviridae.

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__Sources__- Bloom, David C. //et al//. (2008). Third Edition. //Basic Virology//. Blackwell Publishing.

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